Teeth is the most important tool for humans to survive regardless of time and place. It is the tool for survival to chew foods more than tens of millions of times every day until we die. It is the toothbrush and toothpaste that clean this tool and keep it healthy.   It is said that at least over 350 kinds of bacteria or viruses stay in the mouth. What matters is that we can’t remove every bad bacteria and virus only with a toothbrush and toothpaste to clean tooth and keep them in healthy condition. In particular, the toothpaste we use contains abrasives such as silicon dioxide, dental type silica, calcium carbonate and also includes fluorine such as sodium fluoride and sodium phosphate. Besides, paraben has antiseptic effect and preserves the product for long but has some toxic effects such as disturbing the endocrinal hormone system to children etc.   E-SOUP bubble toothpaste to solve two problems the existing toothpaste and toothbrush have at the same time!   Bubble toothpaste is made of nano particle bubble, therefore, (1) it removes bad bacteria and viruses at each corner of mouth, in particular (2) natural materials are used to replace the harmful components of toothpaste. As in this modern day, people can use it anywhere and it plays a role in protecting the gum, its demand is steadily increasing from developed countries and in particular, it becomes the proper toothpaste substitute children can use without concerns